CD59 anticorps (FITC)

N° du produit ABIN319789

Cet anticorps Souris Monoclonal détecte spécifiquement CD59 dans FACS. Il présente une réactivité envers Humain.

Aperçu rapide pour CD59 anticorps (FITC) (ABIN319789)

Antigène: CD59

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD59 est conjugé à/à la FITC

Application: Flow Cytometry (FACS)

Clone: MEM-43

Détail du produit anti-CD59 anticorps (FITC)

Specificité: The antigen binds to C8 and C9 and inhibits assembly of the complement membrane attack complex.

Purification: Purified IgG prepared by affinity chromatography on Protein A

Isotype: IgG2a

Information d'application

Indications d'application: Flow Cytometry (Neat).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.1 mg/mL

Buffer: BS, pH 7.4 containing 0.09 % Sodium Azide as preservative and 1 % BSA as stabilizer.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing. This product is photosensitive and should be protected from light

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur CD59

Antigène: CD59

Autre désignation: CD59

Sujet: CD59 is an LY6 like protein expressed in human lymphoid cells (haemapoietic and non- haemapoietic cells), regulates the action of the complement membrane attack complex on homologous cells. It is a potent inhibitor of the complement membrane attack complex action. It acts by binding to the C8 and/or C9 complements of the membrane attack complex, thereby preventing incorporation of the multiple copies of C9 required for complete formation of the osmolytic pore. This inhibitor appears to be species-specific. CD59 is also involved in signal transduction for T-cell activation complexed to a protein tyrosine kinase. CD59 is an 18-20kD GPI anchored single chain glycoprotein, expressed by virtually all cell types, including leucocytes, platelets and erythrocytes.Synonyms: 20 kDa homologous restriction factor, HRF-20, HRF20, MAC-IP, MAC-inhibitory protein, MACIF, MEM43 antigen, MIC11, MIN1, MIN2, MIN3, MIRL, MSK21, Membrane attack complex inhibition factor, Membrane inhibitor of reactive lysis, Protectin

ID gène: 966

NCBI Accession: NP_000602

UniProt: P13987

Pathways: Système du Complément